Evaluación del efecto analgésico de infusiones intraoperatorias de tramadol y tramadol/lidocaína/ketamina en comparación con morfina/docaína/ketamina en hembras caninas sometidas a ovariohisterectomía
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2010
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Universidad de La Salle. Facultad de Ciencias Agropecuarias. Medicina Veterinaria
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El objetivo de este estudio fue evaluar y comparar el efecto analgésico de infusiones intraoperatorias de tramadol y tramadol/lidocaína/ketamina en comparación con morfina/lidocaína/ketamina en hembras caninas sometidas a ovariohisterectomía. Se utilizaron 30 hembras caninas con una edad promedio y desviación estándar (DE) de 3±2 años, un peso promedio y DE de 19±10 kilos y sin distinción de raza que conformaron 3 grupos aleatorios de 10 animales cada uno: grupo tramadol (grupo T), grupo tramadol/lidocaína/ketamina (grupo TLK) y grupo morfina/lidocaína/ketamina (grupo MLK). Intraoperatoriamente a cada paciente se le evaluaron distintos parámetros hemodinámicos como frecuencia cardíaca (FC), frecuencia respiratoria (FR), presión arterial sistólica (PAS), presión arterial media (PAM), presión arterial diastólica (PAD) y saturación parcial de oxígeno (SPO2), que se interpretaron como parámetros indicadores del estado analgésico en respuesta a los estímulos nociceptivos que percibieron durante la cirugía; estos parámetros se midieron inicialmente sin haber administrado ninguno de los protocolos analgésicos y luego de 15 minutos de administrado el protocolo analgésico se midieron los parámetros cada 2 minutos hasta completar 14 minutos, tiempo promedio en el que finalizaba la cirugía; se consideraron valores estadísticamente significativos valores P
The aim of this study was to evaluate and compare the analgesic effect of intraoperative infusions of tramadol and tramadol/lidocaine/ketamine in comparation with morphine/lidocaine/ketamine in female dogs undergoing ovariohysterectomy. We used 30 female dogs with a mean age and standard deviation (SD) of 3±2 years, average weight and SD of 19±10 kilograms, without distinction of race that formed 3 random groups of 10 animals each: tramadol group (group T), tramadol/lidocaine/ketamine group (group TLK) and morphine/lidocaine/ketamine group (group MLK). Intraoperatively for each patient were evaluated various hemodynamic parameters such as heart rate (HR), respiratory rate (RR), systolic arterial pressure (SAP), mean arterial pressure (MAP), diastolic arterial pressure (DAP) and partial oxygen saturation (PO2S), which were interpreted as indicators of analgesic state parameters in response to nociceptive stimuli perceived during surgery; these parameters were measured initially without the administration of any of the analgesic protocols and after 15 minutes of administered analgesics protocols, parameters were measured every 2 minutes lasting 14 minutes, average completion time of surgery; were considered statistically significant values P
The aim of this study was to evaluate and compare the analgesic effect of intraoperative infusions of tramadol and tramadol/lidocaine/ketamine in comparation with morphine/lidocaine/ketamine in female dogs undergoing ovariohysterectomy. We used 30 female dogs with a mean age and standard deviation (SD) of 3±2 years, average weight and SD of 19±10 kilograms, without distinction of race that formed 3 random groups of 10 animals each: tramadol group (group T), tramadol/lidocaine/ketamine group (group TLK) and morphine/lidocaine/ketamine group (group MLK). Intraoperatively for each patient were evaluated various hemodynamic parameters such as heart rate (HR), respiratory rate (RR), systolic arterial pressure (SAP), mean arterial pressure (MAP), diastolic arterial pressure (DAP) and partial oxygen saturation (PO2S), which were interpreted as indicators of analgesic state parameters in response to nociceptive stimuli perceived during surgery; these parameters were measured initially without the administration of any of the analgesic protocols and after 15 minutes of administered analgesics protocols, parameters were measured every 2 minutes lasting 14 minutes, average completion time of surgery; were considered statistically significant values P
Palabras clave
Analgesia, Hembras caninas, Infusiones, Lidocaína, Ketamina, Tramadol