First report of multiple anthelmintic resistance in nematodes of sheep in Colombia
DOI
https://doi.org/10.1590/0001-3765201620140360
Document Type
Article
Publication Date
3-1-2016
Publication Title
Anais da Academia Brasileira de Ciencias
Abstract
This study aimed to report the presence of parasites resistant to the most used anthelmintic drugs in sheep in Colombia. Four farms (denominated farm 1, 2, 3 and 4) were selected where the animals were not treated with anthelmintics for two months before the trial. Animals with faecal egg count (FEC) above 150 and of different ages were allocated into six groups, each consisting of at least 5 animals. The drugs and dosages used were: ivermectin 1% (0.2 mg/kg), albendazole 25% (5 mg/kg), fenbendazole 10% (5 mg/kg), levamisole 10% (5 mg/kg), and moxidectin 1% (0.2 mg/kg). Anthelmintic efficacy was determined by the FEC reduction test (FECRT) with a second sampling 14 days post-treatment. The efficacy of albendazole and fenbendazole at farm 1 was above 95%, which was different from the others farms. The FECRT indicated the presence of multidrug resistance in the other farms where no tested drugs showed activity higher than 79% (albendazole: 0 to 55%, fenbendazole: 51.4 to 76.6%, ivermectin: 67.3 to 93.1%, levamisole: 0 to 78.1%, and moxidectin: 49.2 to 64.1%). Haemonchus contortus was the predominant (96%) species, followed by a small presence of Trichostrongylus sp. (3%) and Cooperia sp. (1%). Therefore, we report for the first time the existence of multiple anthelmintic resistance in gastrointestinal nematodes of sheep in Colombia.
Volume
88
Issue
1
First Page
397
Last Page
402
ISSN
00013765
Recommended Citation
Gárcia, Carlos M.B.; Sprenger, Lew K.; Benavides Ortíz, Efraín; and Molento, Marcelo B., "First report of multiple anthelmintic resistance in nematodes of sheep in Colombia" (2016). Scopus Unisalle. 376.
https://ciencia.lasalle.edu.co/scopus_unisalle/376
PubMed ID
26871489
Identifier
SCOPUS_ID:84960370550